Health And Fitness

Nitrofurantoin monohydrate/macrocrystals 100 mg capsule .

Nitrofurantoin monohydrate/macrocrystals 100 mg capsule this capsule is mainly used for urinary tract infections. This post provides detailed information about its usage.

 Know the Use of Nitrofurantoin monohydrate/macrocrystals capsules .


Nitrofurantoin monohydrate/macrocrystals 100 mg capsule
Nitrofurantoin monohydrate/macrocrystals 100 mg capsule .

Nitrofurantoin monohydrate/macrocrystals 100 mg capsule is a medication used to treat urinary tract infections UTIs. It contains a combination of two forms of nitrofurantoin monohydrate and macrocrystals.

Nitrofurantoin is an antibiotic that works by interfering with the growth and reproduction of bacteria in the urinary tract. It is commonly used to treat UTIs caused by susceptible bacteria, such as Escherichia coli, Enterococcus species, Staphylococcus aureus and certain strains of Klebsiella and Enterobacter.

The 100 mg capsule is typically taken orally, usually with food, to improve absorption and reduce the risk of stomach upset. The specific dosing instructions will be provided by your healthcare provider and it’s essential to follow them carefully.

Common side effects of nitrofurantoin may include nausea, vomiting, diarrhea, loss of appetite, headache, dizziness, and rash. It’s important to inform your doctor if you experience any severe side effects or allergic reactions.

As with any medication, it’s crucial to take the full course of treatment as prescribed even if your symptoms improve before completion. If you stop taking the medicine too soon the illness might come back or get worse.

Note that this information is not all-inclusive for specialized advice and direction for your unique situation it is always better to speak with a healthcare provider or pharmacist.

Here are some additional details about nitrofurantoin monohydrate/macrocrystals 100 mg capsules:

Mechanism of action 

Nitrofurantoin works by damaging the DNA of bacteria leading to inhibition of bacterial growth and eventual bacterial cell death. It primarily targets bacteria in the urinary tract and has limited effectiveness against bacteria in other parts of the body.


Nitrofurantoin monohydrate/macrocrystals 100 mg capsules are primarily used for the treatment and prevention of urinary tract infections  including acute uncomplicated cystitis  bladder infection caused by susceptible strains of bacteria.


The usual adult dosage for uncomplicated urinary tract infections is one 100 mg capsule taken orally four times a day for 7 days. Your healthcare provider may adjust the dosage based on your specific condition and response to the medication.


Nitrofurantoin monohydrate/macrocrystals capsules should be taken with food or milk to improve absorption and reduce the risk of stomach upset. It’s important to swallow the capsules whole and not crush or chew them as this can affect the release and effectiveness of the medication.

Precautions and contraindications 

Nitrofurantoin should be used with caution in individuals with kidney problems, liver disease, or a history of lung disease. It is contraindicated in individuals with a known hypersensitivity to nitrofurantoin or any component of the formulation. It is not recommended for use during pregnancy near term  38-42 weeks gestation  or in infants under 1 month of age.

Drug interactions 

Nitrofurantoin may interact with certain medications  such as antacids containing magnesium trisilicate  which can decrease the absorption of nitrofurantoin. It’s important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential interactions.


Your healthcare provider may request periodic urine tests during and after the course of treatment to monitor the effectiveness of nitrofurantoin and ensure the resolution of the urinary tract infection.

Adverse effects

Common side effects of nitrofurantoin include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. It may also cause headache, dizziness, drowsiness, and hypersensitivity reactions  rash, itching . Serious adverse effects such as lung problems (pulmonary toxicity  and liver problems hepatotoxicity  are rare but can occur.

Remember to always follow your healthcare provider’s instructions and consult them or a pharmacist for specific information regarding your medication dosage and any concerns you may have.

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